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SlimDiva Academic and Scientific Support References Partial List

The primary ingredients in the powerful combination that makes up the patented  formula  of SlimDiva™, my diet water drink™ (Patent AU2010100778) are pure Mount Tambourine spring water combined with the ripe fruit puree and the pericarp (rind) of the Mangosteen fruit (Garcinia mangostana [Guttiferae]), Brindleberry extract (Garcinia Cambogia) and Prickly Pear extract (Opuntia ficus indica).

Ripe Mangosteen fruit puree gives SlimDiva™, my diet water drink™ its distinct, delicious flavour and has a long history of use as a medical plant, mostly in Southeast Asia. Traditionally mangosteen is famous for its antiinflammatory properties and is used in the treatment of skin infections and wounds. Other applications include the therapy of various conditions such as dysentery, different urinary disorders, cystitis and gonorrhoea. This review highlights the development of this botanical drug into a widely used nutraceutical. Products derived from Garcinia mangostana are now distributed increasingly all over the world. This has given rise to a concomitant increase in research on the phytochemical constituents and biological activity of mangosteen. Central to the biological activity of the species are xanthones.

Mangosteen pericarp (the rind) is an important natural, active ingredient in SlimDiva™ my diet water drink™.  It isa rich source of xanthones (betalains and indicaxanthines) that demonstrate pharmacological activities such as antioxidant, anti-inflammatory and anticancer activities.

Hydroxycitric acid (HCA) is also a constituent  of the dried fruit rind of Mangosteen (Mangostana) and a specific species of Mangosteen – Garcinia Cambogia.  It has been used for centuries throughout Southeast Asia as a food preservative, flavouring agent and carminative. Recent testing shows that this compound may play a role in suppressing appetite, inhibiting fat synthesis and reducing food intake/decrease body weight – without stimulating the central nervous system. In the USA, the extract of this dried fruit rind has been used as a dietary complement for weight management. 

Prickly Pear extract, derived from Opuntia ficus indica (cactus fruit), is the third natural, active ingredient in the patented formula of SlimDiva™ my diet water drink™ (Patent AU2010100778).  It is recognised for its antioxidant (contains betalains) and diuretic properties. Studies support its positive effects on weight management and its role in improving body composition and shape. It has also been shown the help boost immunity.

Below is an indicative list of references to support the health-giving and appetite suppressant claims of Mangosteen, Brindleberry and Prickly Pear.  For more references pertaining to SlimDiva™, my diet water drink™ ingredients and claims, please contact us directly at This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Mangosteen

Carlos A. R. Vasques, Simone Rossetto, Graziele Halmenschlager, Rafael Linden, Eliane Heckler, Maria S. Poblador Fernandez, Jose L. Lancho Alonso (2007) Evaluation of the pharmacotherapeutic efficacy of Garcinia cambogia plus Amorphophallus konjac for the treatment of obesity

Dmitriy Obolskiy, Ivo Pischel, Nisarat Siriwatanametanon, Michael Heinrich (20081 Garcinia mangostana L.: a phytochemical and pharmacological review, Phytotherapy Research Volume 23, Issue 8, Date: August 2009, Pages: 1047-1065

A Loo, Eng Kiat et al, Assay-guided Fractionation Study of alpha-Amylase Inhibitors from Garcinia mangostana Pericarp. Journal of Agricultural and Food Chemistry, October 2007

Sukasmrarn, S. et al, Activity of prenylated xanthones from the fruits of Garcinia mangostana. Chemical and Pharmaceutical Bulletin (Tokyo), July 2003

Jung, HA et al, Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen). Journal of Food and Agricultural Chemistry, March 2006

Matsumoto K et al, Preferential target is mitochondria in alpha-mangostin-induced apoptosis in human leukemia HL60 cells. Bioorgnaic and Medicinal Chemistry, November 2004

Willimas, P et al, Mangostin inhibits the oxidative modification of human low density lipoproteins. Free Radical Research, August 1995

G. Preuss, D. Bagchi, M. Bagchi, C. V. S. Rao, D. K. Dey and S. Satyanarayan
(2004) Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination with niacin-bound chromium (NBC) and a standardized Gymnema sylvestre extract (GSE) on weight loss Diabetes. Obesity and Metabolism 6(3): 171-180

Greenwood MR, Cleary MP, Gruen R, Blase 0, Stern JS, Triscari J, Sullivan AC. Effect of (- )-hydroxycitrate on development of obesity in the Zucker obese rat.Am J Physiol Endocrinol Metab. 1981 ;240:72-8.2.

Leonhardt M, Langhans W. (-) -Hydroxycitrate has long-term effects on feeding behavior, body weight regain and metabolism after body weight loss in male rats. J Nutr. 002;132:1977- 83

Heymsfield SB, Allison DB, Vasselli JR, Pietrobelli A, Greenfield 0, Nunez C. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA. 1998;280: 1596-600

Kriketos AD, Thompson HR, Greene H, Hill JO. (-)-Hydroxycitric acid does not affect energy expenditure and substrate oxidation in adult males in a post-absorptive state. Int J Obes Relat Metab Disord. 1999;23:867-73

Prickly Pear

Knishinsky, Ran, Prickly Pear Cactus Medicine - Treatments for Diabetes, Cholesterol, and the Immune System. ISBN-13: 978-0-89281-149-6 ISBN: 0-89281-149-8

University of Arizona's Department of Obstetrics and Gynecology. Institute of Food Technology, Plant Foodstuff Technology, Hohenheim University, Stuttgart, Germany, Nutritional and medicinal use of Cactus pear cladodes and fruits. September 2006, Frontiers in Bioscience, 11, 2574-2589

Kuti, Joseph O., Texas A & M University, Horticultural Crops & Food Research Laboratory. Antioxidant compounds from four Opuntia cactus pear fruit varieties. March 2003, Elsevier Food Chemistry, 85, 527-533

Knishinsky, Ran, Sample text for Prickly pear cactus medicine: treatments for diabetes, cholesterol and the immune system. Prickly Pear Cactus Medicine, Library of Congress Catalog: number 2004003633

Tesoriere, Luisa et al., Absorption, excretion, and distribution of dietary antioxidant betalains in LDLs: potential health effects of betalains in humans. 2004, American Journal of Clinical Nutrition;2004;80: 941-5